Collameta™

All Age Groups Have Healthy Aging Concerns That Collagen Supports

Healthy aging is no longer just for Boomers – younger consumers are already taking steps toward being proactive about healthy aging. Physical health matters to all generations, younger ones prioritize appearance, while older ones focus on mobility¹. Formulating with collagen has posed challenges. Traditional collagen peptides face absorption challenges due to large molecule size, limiting their effectiveness. Collameta™ offers a highly potent and absorbable collagen tripeptide, simplifying formulation and enhancing efficacy.

What is Collagen?

• Collagen is the primary building block of the body’s essential structures like skin, muscles, bones, tendons and ligaments. 
• As the body ages it starts producing less collagen, causing the skin to dry out and grow thinner, while ligaments, tendons, bones and cartilage become less flexible and brittle over time. 

The Benefits of Using Collagen Tripeptides

• Collagen molecules are too large to be absorbed whole by the body. They need to be broken down into smaller chains of amino acids, known as peptides, for absorption. Collagen peptides are predominantly used in the industry.
• However, even traditional collagen peptides are too large to be absorbed efficiently, requiring larger doses and limiting use in certain applications.
• Collagen tripeptides are even smaller, a sequence of just three amino acids. Their small size allows them to be absorbed directly into the bloodstream for more efficient absorption. In addition, tripeptides have been found to trigger the body to synthesize its own collagen.⁴

Collagen Tripeptides Have Been Clinically Proven to Support Skin, Bone and Joint Health

Stimulates Collagen Synthesis⁴

The oral ingestion of collagen tripeptide had a more positive effect on the collagen synthesis of skin cells than the other samples, suggesting that collagen tripeptides are the most efficient form to ingest. 

Improves Skin Hydration and Elasticity⁶

Improves skin hydration and elasticity, while reducing transepidermal water loss and dry skin.

Preventive/Remedial Effects on Knee Osteoarthritis⁷

Collagen tripeptide administration resulted in a significant improvement of new edema and friction sounds.

May Provide Beneficial Effects on the Bone Healing Process⁸ 

The bone defect area was filled with granulation tissue, a blood clot and a greater number of osteoblasts in the tripeptide-supplemented group.

Ideal for a Wide Range of Applications

Sources: 1. Innova Market Insights, Trends Insider: Top 10 Trends 2023: Trend #3 – Generational Push – Mar 2023 2. Innova Health & Nutrition Survey 2023 (average of Brazil, Canada, China, France, Germany, India, Indonesia, Mexico, Spain, UK, US) 3. ITC Insights 2022, Consumer Supplement User Survey, Collagen Category Report 4. M.E. Nimni et al., Arch. Biochem. Biophys.,122, 292 (1967) Ltd. Jellice Co., Promotion of collagen synthesis (in vivo) - The Central Research Institute of Jellice Co., Ltd. 5. Yamamoto S, Deguchi K, Onuma M, Numata N, Sakai Y. Absorption and Urinary Excretion of Peptides after Collagen Tripeptide Ingestion in Humans. Biol Pharm Bull. 2016;39(3):428-34. 6. Choi, SY., et al. Effects of collagen tripeptide supplement on skin properties: A prospective, randomized, controlled study. Journal of Cosmetic and Laser Therapy, 2014; 16: 132–137., 7. Yamamoto et al., (2015), Effect of collagen tripeptide on knee osteoarthritis in human and animals. Pharmacometrics 89(5/6): 115-124., 8. Hata, S. et al. (2008), Effect of oral administration of high advanced- collagen tripeptide (HACP) on bone healing process in rat. Journal of Hard Tissue Biology 17(1): 17-22.